Compiled by Dr Igor Cernavin, Prosthodontist, Honorary Senior Fellow University of Melbourne School of Medicine, Dentistry and Health Sciences, Director and Cofounder of the Asia Pacific Institute of Dental Education and Research (AIDER), Australian representative of World Federation of Laser Dentistry (WFLD).

Gojkov-Vukelic et al1 examined the effects of treatment of hypersensitive dental cervix with diode laser and found that laser therapy proved to be an extremely safe and effective treatment of cervical dentine hypersensitivity.

Caccianiga and coworkers2 carried out a study to assess if low-level laser therapy enhances the efficiency of orthodontic dental alignment. They concluded that the administration of LLLT might significantly increase the efficiency of orthodontic treatment during dental alignment.

Rosa et al3 carried out a study to verify the accuracy of laser fluorescence for caries detection in vitro and concluded that it had the ability to diagnose occlusal carious lesions in permanent teeth and enamel and dentin caries.

Giannelli and coworkers4 investigated the in vitro efficacy of photodynamic treatment (PDT) with methylene blue (MB) photoactivated with lambda 635nm diode laser and of lambda 405nm violet-blue LED phototreatment for the reduction of bacterial biofilm and lipopolysaccharide (LPS) adherent to titanium surface mimicking the bone-implant interface. They found that non-invasive phototherapy was an attractive alternative in the treatment of peri-implantitis to reduce bacteria and LPS adherent to the titanium implant surface without causing damage to surface microstructure.

Santinoni et al5 conducted a systematic review to evaluate the effectiveness of low-level laser therapy (LLLT) in enhancing maxillofacial area bone repair. They concluded that improvement in bone density can be found when LLLT is applied postoperatively in maxillofacial bony defects. LLLT also seems to promote anti-inflammatory and analgesic effects and accelerate healing, as well as enhance quality of life related to oral health. However, LLLT use protocols need to be standardized before more specific conclusions can be drawn about this subject.

Menem and coworkers6 tested the diagnostic accuracy of a pen-type laser fluorescence (LFpen) device in detecting approximal carious lesions, in posterior permanent teeth, at the cavitation and non-cavitation thresholds, and compared it with that of digital bitewing radiography. They found that the LFpen’s diagnostic performance was accurate and significantly better than digital bitewing radiography in detecting approximal caries lesions, in posterior permanent teeth.

Bayer et al7 compared laser and ozone treatment on oral mucositis in rats and concluded that LLLT is more effective than ozone.

Martins and coworkers8 assessed the efficacy of photobiomodulation (PBM) in the recovery of inferior alveolar nerve (IAN) injury in rats following crushing injury and found that IAN-injured rats which received PBM had a significant improvement of IAN morphometry when compared to IAN-injured rats without PBM.

Comunian et al9 examined the effects of LED and low-intensity laser on the healing of rabbit dental alveoli. Their findings were that photobiomodulation with LASER and LED produced effects, but only the LED demonstrated a beneficial effect.

Javed and coworkers10 carried out a literature review to assess the effectiveness of diode lasers in the management of orofacial pain and concluded that diode laser therapy is more effective in the management of oro-facial pain compared with traditional methods.

Gisler11 wrote an interesting paper explaining how even “hopeless” periodontally involved teeth with very deep pockets of 10mm or more can be saved using laser without open surgery or antibiotics.

Li, Zongbo12 examined the cleaning ability of Er:YAG laser against Enterococcus faecalis in root canals and concluded that it can be effectively used for root canal disinfection without NaClO and Ca(OH)2.

Valente et al13 carried out a review of the literature to assess the increase of temperature following laser irradiation with 810 nm, 980 nm, and 1064 nm diode laser wavelengths, of an implant under conditions that more closely replicate those of the human body. Their conclusion was that use of these diode lasers does not cause a harmful increase in temperature when used under conditions similar to those of the human body.


1. Gojkov-Vukelic, Mirjana; Hadzic, Sanja; Zukanovic, Amila; Pasic, Enes. Application of Diode Laser in the Treatment of Dentine Hypersensitivity. Medical archives (Sarajevo, Bosnia and Herzegovina), 70 (6):466-469; 10.5455/medarh.2016.70.466-469 2016-Dec.
2. Caccianiga, Gianluigi; Paiusco, Alessio; Perillo, Letizia; Nucera, Riccardo; Pinsino, Alberto; Maddalone, Marcello; Cordasco, Giancarlo; Lo Giudice, Antonino. Does Low-Level Laser Therapy Enhance the Efficiency of Orthodontic Dental Alignment? Results from a Randomized Pilot Study. Photomedicine and laser surgery, 10.1089/pho.2016.4215 2017-Mar-02.
3. Rosa, Maria I; Schambeck, Vilson S; Dondossola, Eduardo R; Alexandre, Maria Cm; Tuon, Lisiane; Grande, Antonio J; Hugo, Fernando. Laser fluorescence of caries detection in permanent teeth in vitro: a systematic review and meta-analysis. Journal of evidence-based medicine, 9 (4):213-224; 10.1111/jebm.12227 2016-Nov.

4. Giannelli, Marco; Landini, Giulia; Materassi, Fabrizio; Chellini, Flaminia; Antonelli, Alberto; Tani, Alessia; Nosi, Daniele; Zecchi-Orlandini, Sandra; Rossolini, Gian Maria; Bani, Daniele. Effects of photodynamic laser and violet-blue led irradiation on Staphylococcus aureus biofilm and Escherichia coli lipopolysaccharide attached to moderately rough titanium surface: in vitro study. Lasers in medical science, 10.1007/s10103-017-2185-y 2017-Mar-10.
5. Santinoni, Carolina Dos Santos; Oliveira, Hiskell Francine Fernandes; Batista, Victor Eduardo de Souza; Lemos, Cleidiel Aparecido Araujo; Verri, Fellippo Ramos. Influence of low-level laser therapy on the healing of human bone maxillofacial defects: A systematic review. Journal of photochemistry and photobiology. B, Biology, 169 83-89; 10.1016/j.jphotobiol.2017.03.004 2017-Mar-07.
6. Menem, R; Barngkgei, I; Beiruti, N; Al Haffar, I; Joury, Easter. The diagnostic accuracy of a laser fluorescence device and digital radiography in detecting approximal caries lesions in posterior permanent teeth: an in vivo study. Lasers in medical science, 32 (3):621-628; 10.1007/s10103-017-2157-2 2017-Apr.
7. Bayer, Suzan; Kazancioglu, Hakki Oguz; Acar, Ahmet Huseyin; Demirtas, Nihat; Kandas, Nur Ozten. Comparison of laser and ozone treatments on oral mucositis in an experimental model. Lasers in
8. Martins, Daniel Oliveira; Dos Santos, Fabio Martinez; Ciena, Adriano Polican; Watanabe, Ii-Sei; de Britto, Luiz Roberto G; Lemos, Jose Benedito Dias; Chacur, Marucia. Neuropeptide expression and morphometric differences in crushed alveolar inferior nerve of rats: Effects of photobiomodulation. Lasers in medical science, 10.1007/s10103-017-2181-2 2017-Mar-17.
9. Comunian, Claudio Romulo; Custodio, Antonio Luis Neto; de Oliveira, Leandro Junqueira; Dutra, Carlos Eduardo Assis; D’almeida Ferreira Neto, Milton; Rezende, Cleuza Maria Faria. Photobiomodulation with LED and laser in repair of mandibular socket rabbit: clinical evaluation, histological, and histomorphometric. Oral and maxillofacial surgery, 10.1007/s10006-017-0619-0 2017-Mar-23.
10. Javed, F; Kellesarian, S V; Romanos, G E. Role of diode lasers in oro-facial pain management. Journal of biological regulators and homeostatic agents, 31 (1):153-155; 2017 Jan-Mar.
11. Gisler G. Periodontal therapy of deep localized pockets larger than 9mm. Adjunctive laser irradiation without antibiotics or open surgery. Laser Inernational Magazine of Laser Dentisrty. Volume 9, pages 1-17, issue 1/2017.
12. Li, Zongbo; Fang, Changyun. Bactericidal effects and smear layer removal of Er:YAG-laser radiation against Enterococcus faecalis in root canals. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 42 (3):328-333; 10.11817/j.issn.1672-7347.2017.03.015 2017-Mar-28.
13. Valente, Nicola Alberto; Calascibetta, Antonio; Patianna, Giuseppe; Mang, Thomas; Hatton, Michael; Andreana, Sebastiano. Thermodynamic Effects of 3 Different Diode Lasers on an Implant-Bone Interface: An Ex-Vivo Study With Review of the Literature. The Journal of oral implantology, 43 (2):94-99; 10.1563/aaid-joi-D-16-00188 2017-Apr.